Colborn is a surname, and may refer to:
- Jim Colborn (born 1946), American baseball player
- Nigel Colborn, British Television presenter and gardening expert/writer
- Dr. Theo Colborn (1927–2014), Founder and President of The Endocrine Disruption Exchange
- Joe "Bohannon" Colborn, one half of Chicago radio personality duo Eddie & JoBo
See also
- Colborne Lodge, museum in Ontario, Canada
- Colborne Meredith, Canadian architect
- Colborne Parish, New Brunswick
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