Comana may refer to:
- Comana (Cappadocia), an ancient city in Turkey
 - Comana Pontica, an ancient city of Pontus in Turkey
 - Comăna, a commune in Brașov County, Romania (including the villages of Comăna de Jos and Comăna de Sus)
 - Comana, Constanța, a commune in Constanţa County, Romania
 - Comana, Giurgiu, a commune in Giurgiu County, Romania
 - Comana, a tributary of the Ialomița in Ialomița County, Romania
 - Comana (Olt), a tributary of the Olt in Brașov County, Romania
 
Other
- Comana (genus), a moth genus in the family Limacodidae
 
See also
- Commana
 - Coman (disambiguation)
 - Comanca (disambiguation)
 - Comănești (disambiguation)
 - Komana, a village in the North-West District of Botswana
 
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