David Thornton may refer to:
- David Howard Thornton, American actor
- David Thornton (musician) (born 1978), British euphonium player
- David Thornton (actor) (born 1953), American actor
- David Thornton (American football) (born 1978), linebacker for the Tennessee Titans
- David F. Thornton (1924–2008), member of the Senate of Virginia
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