IRR or Irr may refer to:
Finance
- Implied repo rate, in the futures market
 - Internal rate of return, a profitability metric
 - Iranian rial, currency of Iran by ISO 4217 code
 - Interest rate risk, financial risk from fluctuating interest rates
 
Organisations
- Incident Response Regiment (Australia), an emergency response agency
 - Institute of Race Relations, a policy institute
 - Institute for Religious Research, an apologetics organization
 - Iraqi Republic Railways, a transportation operator
 - South African Institute of Race Relations, a think tank
 
Science and technology
- Image rejection ratio, a radio metric
 - Interrupt Request Register, a register used for managing interrupts in programmable interrupt controllers
 - Internet Routing Registry, a network routing database
 - Irregular galaxy, a galaxy that does not have a distinct regular shape
 
Other
- Incidence rate ratio, a statistic derived from a Poisson regression model
 - Individual Ready Reserve, a personnel status of the United States Military
 - Infusion-related reaction or infusion reaction, a form of systemic inflammatory response syndrome caused by some diseases and drugs
 - Inner Ring Road (disambiguation)
 - Inter-rater reliability
 
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