Isa or ISA may refer to:
Places
- Isa, Amur Oblast, Russia
 - Isa, Kagoshima, Japan
 - Isa, Nigeria
 - Isa District, Kagoshima, former district in Japan
 - Isa Town, middle class town located in Bahrain
 - Mount Isa, Queensland, Australia
 - Mount Isa Airport, IATA airport code "ISA"
 - Isa (river), a river in Belarus
 
People
- Īsā, the name of Jesus in Islam
 - Isa (name), an Arabic name corresponding to Jesus in English
 - Isa, stage name of Lee Chae-young, member of K-Pop group STAYC
 - Isa, female given name, short for Isabel or similar names beginning with Isa- such as Isadora
 - Isa Tengblad (born 1998), Swedish singer using the mononym Isa
 
Arts, entertainment, and media
Fictional entities
- ISA (Days of Our Lives), spy agency in TV series
 - Isa the iguana, in TV series Dora the Explorer
 - Interplanetary Strategic Alliance (ISA), military alliance in videogame saga Killzone
 
Other uses in arts, entertainment, and media
- Isa (Enslaved album), 2004
 - Isa (Zaz album), 2021
 - Isa (film), a 2014 television film
 - Isa, a dance in music of the Canary Islands
 
Computing
- Industry Standard Architecture, a PC computer bus standard
 - Instruction set architecture, the specification for data types, registers, instructions, etc. for a given computer hardware architecture
 - Is-a, a relationship between abstractions in programming
 - Internet Security and Acceleration, a network router, firewall, antivirus program, VPN server and web cache from Microsoft Corporation
 
Education
- Indian Squash Academy, Chennai, India
 - Independent Schools Association (Australia), mainly for sports
 - Independent Schools Association (UK), organisation for independent schools in the United Kingdom
 - Iniciativa de Salud de las Americas, Spanish name for Health Initiative of the Americas
 - Institute for the Study of the Americas, University of London, England
 - Instituto Superior de Agronomia, an agronomy faculty in Lisbon, Portugal
 - Instituto Superior de Arte, an art school in Havana, Cuba
 - International School Amsterdam, the Netherlands
 - International School Augsburg
 - International School of Aleppo, Syria
 - International School of Athens, Greece
 - International School of the Americas, San Antonio, Texas
 - International Studies Association
 - Islamic Saudi Academy
 
Finance
- Income share agreement, a borrowing agreement sometimes used for tuition loans in the United States
 - Individual savings account, class of retail investment arrangement available in the United Kingdom
 - International Standards on Auditing, professional standards for the auditing of financial information.
 - Israel Securities Authority, Israel's national securities regulator
 
Government
- Independent Safeguarding Authority, former UK child protection agency
 - Intelligence Services Act 1994, UK
 - Intelligence Support Activity, of the US Army
 - Internal Security Agency, secret service and counter-espionage agency in Poland
 - International Seabed Authority, for mineral-related activities
 - International Searching Authority, for patents
 - International Solar Alliance
 - Interoperability Solutions for European Public Administrations, EU
 - Invention Secrecy Act
 - Iranian Space Agency
 - Israel Security Agency or Shin Bet, Israel
 - Israel Space Agency
 - Israel State Archives, the national archive of Israel
 - Italian Space Agency
 
Organizations and brands
- Industry Super Australia, the peak body for Industry superannuation funds in Australia
 - Information Systems Associates FZE, an aviation software house
 - Innovative Software Applications, a company taken over by Sorcim in 1982
 - International Federation of the National Standardizing Associations
 - International Seabed Authority
 - International Socialist Alternative, an international association of Trotskyist political parties.
 - International Society of Arboriculture, a non-profit botanical organization
 - International Society of Automation, a non-profit professional organization for engineers, technicians, and students
 - International Sociological Association
 - International Soling Association
 - International Surfing Association, the world governing authority for the sport of surfing
 - Irish Sailing Association, the governing body for sailing in Ireland
 - International Slackline Association
 
Science
- Isosaccharinic acid, a six-carbon sugar acid
 - Intrinsic sympatheticomimetic activity, a term used with beta blockers that are partial agonists
 - Infectious salmon anemia, a viral disease of salmon
 - International Standard Atmosphere, an atmospheric model of the Earth
 - International Seismological Association, former name of the International Association of Seismology and Physics of the Earth's Interior (IASPEI)
 
Entomology
- Isa (moth), a genera of moths.
 
Other uses
- Intelligent speed adaptation, systems to automatically enforce vehicle speed limits
 - International Symbol of Access, blue and white wheelchair symbol
 - ISA Brown, type of chicken
 - Ideological state apparatus, a theory by Louis Althusser
 
See also
- Internal Security Act (disambiguation)
 - Isaz, the "I" rune in the Scandinavian runic alphabet
 - Issa (disambiguation)
 - Isha (disambiguation)
 - ESA (disambiguation)
 
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