Jessica Moore may refer to:
- Jessica Moore (actress) (born 1967), Italian actress in the 1987 film Eleven Days, Eleven Nights
- Jessica Moore (basketball) (born 1982), WNBA player for the Indiana Fever
- Jessica Moore (journalist) (born 1982), American journalist
- Jessica Moore (tennis) (born 1990), Australian tennis player
- Jessica Care Moore (born 1971), American poet
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