John Mackey may refer to:
- John Mackey (American football) (1941–2011), American football tight end
 - John Mackey (businessman) (born 1953), founder of Whole Foods Market
 - John Mackey (composer) (born 1973), American composer of classical concert music
 - John Mackey (hurler) (1914–1989), Irish athlete in the sport of hurling
 - John Mackey (politician) (1863–1924), Australian politician
 - John Mackey (Roman Catholic bishop) (1918–2014), Bishop of Auckland (1974-1983)
 - John C. Mackey, American football coach
 - Jack Mackey (John Bernard MacKey, 1922–1945), recipient of the Victoria Cross
 - John Mackey (Tyler) (1882–1962), Irish hurler
 
See also
- Jack McKay (disambiguation)
 - John Mackay (disambiguation)
 - John Mackie (disambiguation)
 - John McKay (disambiguation)
 
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