Karns may refer to:
- Places
- Karns, Tennessee, United States
- Karns City, Pennsylvania, United States
- Karns, Pennsylvania, United States
- People
- Roscoe Karns (1891–1970), American actor
- Stephen Karns, American lawyer
- Todd Karns (1921–2000), American actor
- Virginia Karns (1907–1990), American singer and actress
- Companies
- Karns Quality Foods, a supermarket chain in Pennsylvania
See also
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