Route 213 or Highway 213 can refer to:

Canada

• Manitoba Provincial Road 213
• Newfoundland and Labrador Route 213
• Nova Scotia Route 213
• Prince Edward Island Route 213
• Quebec Route 213

China

• China National Highway 213

Costa Rica

• National Route 213

Ireland

• R213 regional road

Japan

• Japan National Route 213

United States

• U.S. Route 213 (former)
• Alabama State Route 213
• California State Route 213
• Connecticut Route 213
• Florida State Road 213 (former)
• Georgia State Route 213 (former)
• Illinois Route 213 (former)
• Kentucky Route 213
• Maine State Route 213
• Maryland Route 213
• Massachusetts Route 213
• M-213 (Michigan highway) (former)
• Missouri Route 213
• Montana Secondary Highway 213
• New Mexico State Road 213
• New York State Route 213
• North Carolina Highway 213
• Ohio State Route 213
• Oregon Route 213
• Pennsylvania Route 213
• South Carolina Highway 213
• Tennessee State Route 213
• Texas State Highway 213
  • Texas State Highway Loop 213
  • Texas State Highway Spur 213
• Utah State Route 213 (former)
• Virginia State Route 213
• Washington State Route 213 (unbuilt)
• Wisconsin Highway 213
• Wyoming Highway 213