MBE may refer to:
Academic qualifications
- Master of Bioprocess Engineering
 - Master of Bioethics
 - Master of Bioscience Enterprise
 - Master of Business Engineering
 - Master of Business Economics
 
Science and technology
- The Mid-Brunhes Event, a climatic change at around 430,000 years ago
 - Mode-based Execution Control, an x86 virtualization technology
 - Model-based enterprise, a manufacturing strategy where a 3D model of a product is used to guide its life cycle
 - Molecular-beam epitaxy, a thin-film crystal growth technique
 - Molecular Biology and Evolution, a journal
 - Multi-band excitation, a series of speech coding standards
 - Multibeam echosounder, a device used to map ocean floors
 
British honours
Other uses
- Mail Boxes Etc., a global chain of retail business service centers
 - Management by exception, a style of business management
 - Minority business enterprise, a classification of business
 - Morning Becomes Eclectic, a radio program
 - Multistate Bar Examination, an exam administered to most prospective American lawyers
 - Monbetsu Airport's IATA code
 
See also
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