Malyshev (masculine) or Malysheva (feminine) may refer to:
- Malyshev Factory, a heavy equipment factory in Ukraine
 - Vyacheslav Malyshev (1902-1957), Soviet politician buried in the Kremlin Wall Necropolis
 - Yury Malyshev, several people
 - Malysheva, several inhabited localities in Russia
 
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