Nichelle is a given name. Notable people with the name include:
- Nichelle Nichols (1932–2022), American actress, singer, and voice artist
- Nichelle Prince (born 1995), Canadian soccer player
- Nichelle Tramble Spellman (born 1967), American television producer and writer
See also
- Nischelle Turner, American reporter and correspondent
- Michelle (name)
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