Sadleir may refer to:
People with the surname
- Franc Sadleir (1775–1851), Irish academic
 - James Sadleir (c.1815 – 1881), Irish financier and politician
 - John Sadleir (1813–1856), Irish financier and politician
 - Lynette Sadleir (b. 1963), Canadian-born swimmer
 - Michael Sadleir (1888–1957), British author and bibliophile
 - Ralph Sadleir (1579–1661), English landowner
 - Thomas Sadleir (died 1607) (c.1536–1607), English landowner and politician
 - Thomas Sadleir (1882–1957), Irish genealogist and herald
 - Lionel Sadleir-Jackson (1876–1932), British army officer
 
Places
See also
- Sadleirian Professor of Pure Mathematics, University of Cambridge
 - Saddler (disambiguation)
 - Sadler (disambiguation)
 - Sadlier, a surname
 
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