Sanitarium or sanatorium may refer to:

Facilities

• Sanatorium, medical facility for long-term illness, often associated with treatment of tuberculosis before antibiotics
• Sanatorium (resort), facility with spa and medical services, as known in Russia, Ukraine, and other former Soviet Union republics
• Battle Creek Sanitarium, American health resort founded in 1866
• Sanitarium Health and Wellbeing Company, major food company in Australia and New Zealand

Film and video games

• The Sanitarium (film), a 1910 American silent comedy short starring Fatty Arbuckle
• Sanitarium (video game), American 1998 point-and-click adventure
• Sanitarium (film), a 2013 American horror anthology film

Localities

• Sanitarium, California, American unincorporated community in Napa County
• Sanatorium, Mississippi, American village near Magee

Music

• "Welcome Home (Sanitarium)", 1986 song by American heavy metal band Metallica
• Sanatorium (band), North Macedonia thrash metal band from Skopje, formed in 1987