Seiler is a surname. Notable people with the surname include:
- Alexander Seiler I (1819–1891), Swiss Hotel Pioneer
- Hermann Seiler (1876–1961) Swiss Hotel Pioneer & Politician
- Jack Seiler (born 1963), American politician and Mayor of Fort Lauderdale, Florida
- Kerim Seiler (born 1974), Swiss artist and architect
- Lewis Seiler (1890–1964), American film director
- Paul Seiler (1945–2001), American football player
- Reinhard Seiler (1909–1989), German Luftwaffe pilot
- Robert Eldridge Seiler (1912–1998), American judge on the Missouri Supreme Court
- Sebastian Seiler (1810–1890), German journalist
- Sonny Seiler (1933–2023), American attorney and bulldog owner
See also
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