Siku may refer to:
- Siku (instrument), a kind of pan flute from the Andes
 - Siku (Bolivia), a mountain in the Bolivian Andes
 - Siku Toys, a German brand of toy vehicles
 - Siku (comics), an artist
 - Siku (polar bear), a bear cub who became an overnight online sensation
 - Siku Quanshu, a compendium of Chinese literature completed in 1782
 - Secoo, Chinese online retailer
 - Siku Allooloo, indigenous writer
 - Siku Ya Bibi (Day of the Lady)
 - Siku Njema, a Swahili novel
 
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