Sophonisba (fl. 203 BC) was a Carthaginian noblewoman.
Sophonisba or Sofonisba may also refer to:
Arts and entertainment
- The Wonder of Women, or the Tragedy of Sophonisba, a 1606 tragedy by John Marston
 - Sophonisba (Lee play), a 1675 tragedy by Nathaniel Lee
 - Sophonisba (Thomson play), a 1730 tragedy by James Thomson
 - Sophonisbe (tragedy), by Voltaire, 1770
 - Sophonisbe, a 1663 dramatic work by Pierre Corneille
 - Sofonisba (Mantegna), a 15th-century painting in the Exemplary Women of Antiquity set by Andrea Mantegna
 - Sofonisba, a 1762 opera by Tommaso Traetta
 
People
- Sofonisba Anguissola (c. 1532 – 1625), Italian Renaissance painter
 - Sophonisba Angusciola Peale (1786–1859), American ornithologist and artist
 - Sophonisba Breckinridge (1866–1948), American activist and Progressive Era social reformer
 
See also
- All pages with titles containing Sophonisba
 
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