Xan may refer to:
- Xan (given name), a diminutive name derived from Alexander, Alexandra or Alexandria, or Galician for John
- Xan (vodka), produced by the Azerbaijani company Vinagro
- Xan (Baldur's Gate), a companion character from the Baldur's Gate series of computer games
- The final boss from computer game Unreal Tournament and sequels
- A book by Patrick Tilley on alien invasion
- Slang for the drug Xanax
- The rap artist Lil Xan
- An alternate spelling of Khan (title)
- A character from the novel The Children of Men by P. D. James
- A legendary and ancient race in the popular MMORPG Anarchy Online
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