Yuk may refer to:
- Mr. Yuk, a trademarked cartoon graphic image, widely employed in the United States in labeling of substances that are poisonous if ingested
 - Yuk, a sophomore at the United States Military Academy
 - Yuk Yuk's, a national comedy club chain in Canada, owned and established by former stand-up comedian Mark Breslin
 - Yuk, a Korean surname derived from Lu (surname 陆)
- Yuk Young-soo, former first lady of South Korea
 
 - The Ainu word for the Yezo sika deer.
 
See also
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